Here, we use data from 379,768 UK Biobank (UKB) participants of European ancestry to assess the pathogenicity and penetrance of putatively clinically important rare variants. Finally, we refute the previous disease association of RNF135 in developmental disorders. In conclusion, this study shows that very large population based studies will help refine our understanding of the pathogenicity of rare genetic variants..
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Military officials have denied any consequential effects on most troops, but after Defense Department testing, news reports and congressional hearings, the Department of Veterans Affairs asked the Institute of Medicine to conduct its own study on long term health effects. Population, the study said. The exceptions were pollutants that could not attributed primarily to the burn pit.
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