Sen. Bernie Sanders (I Vt.), the chair of the committee, joined some GOP colleagues in questioning Tanden about some inflammatory comments she previously made on Twitter. “Your attacks were not just made against Republicans,” he said. Reporting guidelines have been published for various research designs,9 and these contain many items that are also relevant to genetic risk prediction studies. In particular, the guidelines for genetic association studies (STREGA) have relevant items on the assessment of genetic variants, and the guidelines for observational studies (STROBE) have relevant items about the reporting of study design. The guidelines for diagnostic studies (STARD) and those for tumour marker prognostic studies (REMARK) include relevant items about test evaluation; the REMARK guidelines also have relevant items about risk prediction.5 10 11 12 However, none of these guidelines are fully suited to genetic risk prediction studies, an emerging field of investigation with specific methodological issues that need to be addressed, such as the handling of large numbers of genetic variants (from 10s to 10000s) and flexibility in handling such large numbers in analyses.

Fewer employees will mean crews collecting leaves will be smaller. Smaller crews means collection speed will be slower. And slower collection means fewer opportunities to have leaves picked up at the curb. The industry has a long history of being both ageist and sizeist. He may well be the victim this time, but one wishes he’d used his stature and knowledge of what goes on inside fashion’s glossy realm to consider the wider moral and financial implications of the industry’s continued skittishness about age and size. His hurt is important, but what comes down to an assault on Wintour’s communication style is petty..

Also some personal responsiblity in the equation is necessary. Currently the attitude is that if a car is involved in any accident it is the cars fault. Even if it is legally not the car drivers fault the media and public always play it as the car was some how negligent and that is the important part of the equation..

The PFC has spent the last year carefully working on this process, including designing various methods for community members to provide input. The PFC committed to listening to all residents in the City of Madison, including those who have the greatest challenges to providing feedback. For instance, the PFC received oral comments over the course of multiple meetings from various groups and individuals.