Macrophages also play a crucial role in orchestrating immune responses to biomaterials used in the fabrication of implantable devices and drug delivery systems. To assess the impact of different surface chemistries on macrophage polarisation, human monocytes were cultured for 6 days on untreated hydrophobic polystyrene (PS) and hydrophilic O2 plasma etched polystyrene (O2 PS40) surface. Our data clearly show that monocytes cultured on the hydrophilic O2 PS40 surface are polarised towards an M1 like phenotype, as evidenced by significantly higher expression of the pro inflammatory transcription factors STAT1 and IRF5.
Bp: Liam GallagherSign up to FREE daily email alerts from mirror celebsSubscribe We will use your email address only for sending you newsletters. Please see ourPrivacy Noticefor details of your data protection rightsThank you for subscribingWe have more newslettersShow meSee our privacy noticeCould not subscribe, try again laterInvalid EmailLiam Gallagher is marrying his long term All Saints girlfriend Nicole Appleton today.The showbiz couple, who have been together for nearly eight years, were keen to keep the wedding quiet.Liam brother Noel will be at the small gathering, as well as Nicole sister Natalie and her husband Liam Howlett of the Prodigy.Speaking exclusively to the Mirror, Nicole, 32, said: “It important to me and I love the idea of being married.””A few of my friends are getting married and it such a stress.”It becomes like a circus and people don dare mention the w word.”Nicole has been credited with taming the Oasis wildman.She said: “When I see him strutting on to the stage I don recognise him.””He like a lion tamer and with a crack of the whip he controls the fans.”He can do that to me. At home, I the lion tamer.