Taken from the introduction:One of the main aims of this study is to give a clear and coherent view of the main events, and to examine the role played by the Nottinghamshire miners in the strike of 1984 85. It will also critically analyse some of the more negative and inexact accounts of their role which have painted them as the anti heroes in the 1984 85 strike. Basically this thesis will try and make a case that the majority of Nottinghamshire miners acted in line with their established ‘custom and practice’.

High throughput screens of kinase and phosphatase inhibitor libraries using the nuclear foci assay and CLCNI splicing construct assay yielded two positive hits: protein kinase C inhibitors designated in the compound library as D8 (hypericin) and D9 (Ro 31 8220).The second part of this thesis deals with the confirmation of compound hits obtained from the primary screen. I examined two aspects: mutant DMPKtranscript entrapment in nucleus and splicing defects associated with the disease. A BpmJ restriction assay was used to test the effect of compounds on mutant DMPK transcripts showed that both D8 and D9 were unable to release the mutant transcript into the cytoplasm.

Leaders of rival Palestinian factions began Egyptian brokered reconciliation talks in Cairo on Monday to try to heal long standing internal divisions, ahead of planned Palestinian elections later this year. Egypt has tried in vain for 14 years to reconcile Palestinian President Mahmoud Abbas nationalist Fatah faction and its bitter rival Hamas, the armed Islamist movement that opposes any negotiations with Israel. No Palestinian elections have been held in Gaza, the West Bank and East Jerusalem for 15 years..

Coincidently Madson is a registered nurse specializing in heart health at Franciscan Hospital. He said they’ve stayed busy at work lately but that particular day was slow and he had the opportunity to go home early. He decided to head to the gym, which just so happened to be the same time McIver was there..

The humdrum of life may make each day the same but there are certain things that I look forward to with renewed eagerness that form a mosaic of interesting visuals in my mind with indefinite appeal. Almost daily I see a short swarthy man sporting a ray ban (even when there is no sun), ripping a packet of some savoury item to feed pigeons, crows and maynas at a footpath. After he empties the pack, he brings his hands together in Namaste and faces the sun offering a silent prayer, some gratitude while the birds all around him peacefully enjoy the morning treat.