Causal but, rather, two styles of descriptive modeling, one interpretable, the other uninterpretable. The former is exemplified by predictive regression models, and the latter by modern big data algorithms such as deep learning, BART, trees and forests. The former carries the potential of being interpreted as causal, the latter leaves no room for such interpretation; it describes the prediction process chosen by the analyst, not the data generation process chosen by nature.

Thus new legislation in 2004 introduced a new procedure for these projects: competitive dialogue. However, commentators have identified possible problems with competitive dialogue and there are numerous legal grey areas.The research examines the way in which the new legal framework for competitive dialogue is applied to PPPs in the UK, and actors’ perceptions of the framework. It seeks to identify perceived positive aspects of competitive dialogue in facilitating best practice; perceived problems, including any legal uncertainty and constraints on best practice; strategies to conduct the process within the constraints; and the factors that influence compliance and approach to legal risk.The research adopts a socio Iegal approach, combining analysis of the legal rules, with a study of the literature on theories of regulation and enforcement, and qualitative interviews with legal advisors, procurement officers, and policymakers..

An isochronous sequence is a series of repeating events with the same inter onset interval. A common finding is that as the length of a sequence increases, so does temporal sensitivity to irregularities that is, the detection of deviations from isochrony is better with a longer sequence. Several theoretical accounts exist in the literature as to how the brain processes sequences for the detection of irregularities, yet there remains to be a systematic comparison of the predictions that such accounts make.

Of the 11 C2 non responders, nine met 2NDNR criteria (incidence=12%) and tested positive for anti rituximab antibodies. Lack of concomitant immunosuppressant and higher pre rituximab plasmablasts predicted 2NDNR. Five were switched to ocrelizumab/ofatumumab, and all depleted and responded..

NEU officials want to return to schools when it is safe, but have rejected the Government proposals at every turn. They recently claimed that vaccinating teachers would not be enough to get back to the classroom. Since the schools have closed they have said that it is an “unrealistic expectation” for teachers to do every lesson as a livestream.