Reporting guidelines have been published for various research designs,9 and these contain many items that are also relevant to genetic risk prediction studies. In particular, the guidelines for genetic association studies (STREGA) have relevant items on the assessment of genetic variants, and the guidelines for observational studies (STROBE) have relevant items about the reporting of study design. The guidelines for diagnostic studies (STARD) and those for tumour marker prognostic studies (REMARK) include relevant items about test evaluation; the REMARK guidelines also have relevant items about risk prediction.5 10 11 12 However, none of these guidelines are fully suited to genetic risk prediction studies, an emerging field of investigation with specific methodological issues that need to be addressed, such as the handling of large numbers of genetic variants (from 10s to 10000s) and flexibility in handling such large numbers in analyses.

In a roadmap unveiled Tuesday with top public health officials, Gov. Gavin Newsom said he will not lift his shelter in place order until adequate suppression and mitigation measures are in place to prevent future flare ups. That means tracking down the sick and isolating clusters of new infections, arming hospitals with adequate equipment and setting new guidelines for schools and businesses to reopen..

Hydraulic fracturing is a method of oil extraction in which fluid is injected into cracks in rock formations to enlarge them so more oil and gas can flow into a drilling wellbore, from which it is extracted. A similar method, acidizing, uses hydrochloric acid or other chemicals to dissolve the rocks for the same result. A very well attended public meeting was held recently to discuss the methods..

Everyone in the food service industry is constantly being pounded with regulations, loss of revenue, loss of pay, loss of life, and all the things that have been impacting our industry and the people who support it. If a server forgets something, if the restaurant is out of something, which is usually not their fault, if the experience was not perfect, please put in perspective that your life is not even close to being devastated as probably the hands that serve you. So be kind, greet your server with a smile, tip well (25% or better) and understand that your dining experience is being served by those most affected by this pandemic.”Debra Kue, president, Thai Chef in Grand Rapids: “It is absolutely essential that customers also treat one another with respect and equity.